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The principal aim of this thesis is to develop a simple software tool, Visvac, for the representation and analysis of bacterial genomes using the BioVista system. This thesis attempts to create a software tool through which researchers can quickly annotate their genomes, create simple views, and quickly access a large number of reference sequences.
Research has shown that scientists use various sources, including the Internet, to research and evaluate medical discoveries. Most bacteria, however, are far too large for a single researcher to track down and study, and thus, they have yet to attract the attention of the larger scientific community. In order to make more bacterial projects available to the scientific community, a new online system of curated reference sequences has been developed. This system, which is called Visvac, is intended to showcase reference sequences to the scientific community.
The best known resistance genes encode efflux pumps that actively export antibiotics from the cell. These pumps often involve the cell membrane, as efflux pumps are divided by their location. In general, genes that encode efflux pumps have been developed for export of a wide range of antibiotics, and sometimes combinations of antibiotics, making them important for the treatment of a wide variety of bacterial infections in patients. Genes that encode efflux pumps have also been shown to be responsible for classifying bacteria into categories called multidrug resistant bacteria.
The Aquatic Animal Genetic Resource Database (Aquagene) is an online database with a collection of one hundred and eighty genetic resources from freshwater fish species. The Aquagene database aims to develop and maintain an Aquatic Genetic Resource Database. It will integrate information on genetic resources and support efficient and reliable knowledge management. The information provided in this database will be of interest to all those working in the field of aquatics with the aim of providing up to date information made accessible and available to anyone. By sharing information, the Aquagene collection will also help to advance knowledge about the genetics of fish species and biodiversity preservation. d2c66b5586
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